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Lipopolysaccharide of the outer membrane of gram-negative cell walls is called ______.


A) exotoxin
B) endotoxin
C) enterotoxin
D) leukocidin
E) hemolysin

F) C) and D)
G) B) and D)

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The subjective evidence of disease sensed by the patient is termed a/an ______.


A) syndrome
B) symptom
C) sign
D) pathology
E) inflammation

F) A) and E)
G) B) and E)

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Based on new information from the Human Microbiome Project, the human body typically begins to be colonized by its normal biota


A) before birth, in utero.
B) during and immediately after birth.
C) when a child first goes to school.
D) when an infant gets its first infectious disease.
E) during puberty.

F) A) and D)
G) B) and E)

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The term infection refers to


A) microorganisms colonizing the body.
B) contact with microorganisms.
C) contact with pathogens.
D) pathogens penetrating host defenses.

E) C) and D)
F) A) and B)

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The total number of deaths in a population due to a disease is the ______ rate.


A) morbidity
B) mortality
C) incidence
D) endemic
E) pandemic

F) A) and D)
G) B) and E)

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The skin's resident biota are localized to only the outermost superficial layer of the epidermis.

A) True
B) False

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The number of new cases of a disease in a population over a specific period of time compared with the healthy population is the ______.


A) mortality rate
B) morbidity rate
C) incidence rate
D) prevalence rate
E) epidemic rate

F) A) and D)
G) C) and D)

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An infectious agent that originates from outside the body is called ______.


A) exogenous
B) an exotoxin
C) an enterotoxin
D) endogenous
E) axenic

F) A) and B)
G) D) and E)

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When would Koch's postulates be utilized?


A) to determine the cause of a patient's illness in a hospital microbiology lab
B) to develop a new antibiotic in a pharmaceutical lab
C) to determine the cause of a new disease in a microbiology research lab
D) to formulate a vaccine against a new pathogen in a genetic engineering lab
E) whenever the scientific method cannot be used to investigate a microbiological problem

F) B) and C)
G) A) and B)

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The stage of an infectious disease when specific signs and symptoms are seen and the pathogen is at peak activity is the ______.


A) prodromal stage
B) convalescent stage
C) incubation period
D) period of invasion

E) All of the above
F) B) and D)

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Animals that participate in the life cycles of pathogens and transmit pathogens from host to host are ______.


A) fomites
B) aerosols
C) mechanical vectors
D) droplet nuclei
E) biological vectors

F) D) and E)
G) C) and E)

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In the movie "Contagion", one person who has become infected with a recombinant pathogenic virus spreads it to a large number of people with whom she comes into contact.Those people then spread it to others, and, before you know it, the disease has spread all over the world.This is an example of a _______ epidemic.


A) point-source
B) common-source
C) propagated
D) endemic

E) B) and C)
F) A) and C)

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Exotoxins ______.


A) are secreted by pathogenic organisms
B) are bound to the membrane of pathogenic organisms
C) are bound to the cell wall of pathogenic organisms
D) cause more damage than endotoxins
E) are host specific

F) A) and B)
G) B) and D)

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The prevalence rate of tuberculosis in one particular county in Texas is 7/1000 people, while the incidence rate for 2011 is 2/1000 people.Analyze this data and summarize the situation.


A) The data were collected incorrectly because the two values should match.
B) Incidence rate should really be higher than prevalence rate because it includes all new cases for the year.
C) Prevalence rate is higher than incidence rate because the number of people still alive with tuberculosis is higher because of better treatments.
D) Prevalence rate and incidence rate cannot be determined for the same disease.

E) A) and B)
F) A) and C)

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All of the following genera are considered resident biota of skin sites except ______.


A) Escherichia
B) Staphylococcus
C) Corynebacterium
D) Micrococcus
E) Candida

F) A) and B)
G) B) and E)

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An example of an epigenetic change is


A) a microbe secreting hyaluronidase to break down host hyaluronic acid.
B) Clostridium tetani secreting the exotoxin tetanospasmin.
C) a gram-negative organism releasing lipopolysaccharide from its cell wall upon lysis.
D) a microbe that can induce changes in host DNA, resulting in suppression of defenses or weakening of individual cells.

E) None of the above
F) A) and D)

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A sign is


A) an objective indication of disease.
B) a subjective indication of disease.
C) measurable by health care personnel.
D) malaise and body aches.
E) an objective indication of disease that is measurable by health care personnel.

F) B) and D)
G) C) and D)

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Normal biota includes each of the following except ______.


A) bacteria
B) fungi
C) protozoans
D) viruses
E) All of the choices are correct.

F) A) and B)
G) B) and D)

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The difference between the terms pathogenicity and virulence is that


A) pathogenic organisms cause disease, virulent organisms do not.
B) virulent organisms cause disease, pathogens do not.
C) pathogens cause disease and their virulence describes the degree of pathogenicity.
D) virulent organisms cause disease and their pathogenicity describes the degree of disease manifestations.

E) A) and B)
F) C) and D)

Correct Answer

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A fetus can get an infection when a pathogen in the mother's blood is capable of crossing the placenta to the fetal circulation and tissues.

A) True
B) False

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